Amygdala and Hippocampal Volumes in Relatives of Patients With Bipolar Disorder: A High-Risk Study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F09%3A00002269" target="_blank" >RIV/00216208:11120/09:00002269 - isvavai.cz</a>
Alternative codes found
RIV/00023752:_____/09:43914555
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
Amygdala and Hippocampal Volumes in Relatives of Patients With Bipolar Disorder: A High-Risk Study
Original language description
Bipolar disorders (BD) have a strong genetic underpinning, yet no biological vulnerability markers for BD have yet been identified. To test whether amygdala or hippocampal volumes represent an endophenotype for BD, we measured mesiotemporal volumes in young affected and unaffected relatives of patients with BD (high-risk design). Method: High-risk participants (aged 15 to 30 years) were recruited from families multiply affected with BID. They included 20 affected and 26 unaffected offspring of parents with primary mood disorders, matched by age and sex with 31 control subjects without a personal or family history of psychiatric disorders. Amygdala and hippocampal volumes were measured on 1.5 Tesla 3-dimensional anatomical magnetic resonance images using standard methods. Results: We found comparable amygdala and hippocampal volumes among unaffected relatives, affected high-risk patients, and control subjects. The exclusion of 6 medicated patients did not change the results. There were
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
—
Result continuities
Project
—
Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Canadian Journal of Psychiatry-Revue Cannadiene de Psychiatrie
ISSN
0706-7437
e-ISSN
—
Volume of the periodical
54
Issue of the periodical within the volume
11
Country of publishing house
CA - CANADA
Number of pages
8
Pages from-to
—
UT code for WoS article
000272058900005
EID of the result in the Scopus database
—