Targeting out-of-hospital cardiac arrest: The effect of heparin administered during cardiopulmonary resuscitation (T-ARREST)

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003192" target="_blank" >RIV/00216208:11120/11:00003192 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/11:10105879 RIV/00179906:_____/11:10105879
Result on the web
<a href="http://www.signavitae.com/articles/original-articles/178-targeting-out-of-hospital-cardiac-arrest-the-effect-of-heparin-administered-during-cardiopulmonary-resuscitation-t-arrest" target="_blank" >http://www.signavitae.com/articles/original-articles/178-targeting-out-of-hospital-cardiac-arrest-the-effect-of-heparin-administered-during-cardiopulmonary-resuscitation-t-arrest</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Targeting out-of-hospital cardiac arrest: The effect of heparin administered during cardiopulmonary resuscitation (T-ARREST)
Original language description
Heparin administration during cardiopulmonary resuscitation (CPR) may prevent activation of coagulation after successful resuscitation for out-of-hospital cardiac arrest (OHCA). We hypothesize that such an approach is not associated with an increased rate of bleeding, but it has not been evaluated. We performed a pilot randomized clinical study assessing the safety of intra-arrest heparin administration in OHCA patients with suspected acute myocardial infarction (AMI) and its impact on their prognosis.OHCA patients were randomized during CPR to 10 000 units of intra-arrest intravenous heparin (Group H) or to treatment without heparin (Group C). The occurrence of major bleeding and the presence of a favourable neurological result 3 months after OHCA, were analyzed. Out of 88 randomized patients, AMI was subsequently confirmed in 63 of them (71.6 %). There were 30 patients in group H and 33 in group C. No major bleeding event was observed in either group. Return of spontaneous circulati
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Project
<a href="/en/project/NS10383" target="_blank" >NS10383: New therapeutic procedures during cardiopulmonary resuscitation in animal model of ventricular fibrillation</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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