Sex differences in social interaction of methamphetamine-treated rats
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003220" target="_blank" >RIV/00216208:11120/11:00003220 - isvavai.cz</a>
Alternative codes found
RIV/67985823:_____/11:00370382
Result on the web
<a href="http://dx.doi.org/10.1097/FBP.0b013e32834afea4" target="_blank" >http://dx.doi.org/10.1097/FBP.0b013e32834afea4</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/FBP.0b013e32834afea4" target="_blank" >10.1097/FBP.0b013e32834afea4</a>
Alternative languages
Result language
angličtina
Original language name
Sex differences in social interaction of methamphetamine-treated rats
Original language description
Our previous study showed that single injection of methamphetamine decreases social interaction (SI) in a dose-dependent manner that was further affected by stressful environment conditions. The aim of this study was to examine the effect of methamphetamine and its interaction with gonadal hormones on SI. Adult male and female rats were gonadectomized and assigned to testosterone-treated and oil-treated groups in male rats and estradiol-treated and oil-treated groups in female rats, respectively. Hormones were administered 30 min before each habituation in the open field. All four hormonal groups were further divided to control (without injection), saline (1 ml/kg saline injection), and methamphetamine (1 mg/kg) groups. Injections were applied 30 min before the SI test. The total duration and the total number of SI and nonsocial behavioral patterns were assessed. This study showed that an acute methamphetamine administration in a dose of 1 mg/kg decreased different types of SI in both
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Behavioural Pharmacology
ISSN
0955-8810
e-ISSN
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Volume of the periodical
22
Issue of the periodical within the volume
7
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
617-623
UT code for WoS article
000294948200001
EID of the result in the Scopus database
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