Platelet-derived chemokines, PF-4 and RANTES, are significantly increased in hemodynamically significant degenerative aortic stenosis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003402" target="_blank" >RIV/00216208:11120/11:00003402 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14310/11:00061085

Result on the web

<a href="http://dx.doi.org/10.1016/j.ijcard.2011.08.021" target="_blank" >http://dx.doi.org/10.1016/j.ijcard.2011.08.021</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijcard.2011.08.021" target="_blank" >10.1016/j.ijcard.2011.08.021</a>

Result language

angličtina

Original language name

Platelet-derived chemokines, PF-4 and RANTES, are significantly increased in hemodynamically significant degenerative aortic stenosis

Original language description

The study focused on platelet-derived chemokines, platelet factor 4 (PF4,CXCL4) and RANTES (CCL5), in symptomatic degenerative aortic stenosis. Methods The study group was comprised of 124 consecutive patients (mean - SD age 71.6-9.5 years, 63.6% men) being considered for aortic valve replacement for symptomatic degenerative trileaflet valvular AoS, and were undergoing cardiac catheterization. Blood samples were collected from the bulbus of the aorta at the beginning of catheterization. Laboratory values for serum levels of PF4 and RANTES were compared between: i) group A (N = 64) patients with AoS and without coronary artery disease (CAD), ii) group B (N = 60) patients with AoS and with stable CAD, and iii) group C (N = 42) control group; patients without AoS and without CAD. Linear regression analyses were performed to adjust the compared groups for variables that might influence platelet activation. Degenerative AoS without CAD and also with CAD had significantly elevated serum conc

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

—

Project

—

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Cardiology

ISSN

0167-5273

e-ISSN

—

Volume of the periodical

152

Issue of the periodical within the volume

2

Country of publishing house

IE - IRELAND

Number of pages

3

Pages from-to

273-275

UT code for WoS article

—

EID of the result in the Scopus database

—