Rationale and design of The Coronary Artery Bypass Grafting Surgery Off or On Pump Revascularization Study: A large international randomized trial in cardiac surgery

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F12%3A00003517" target="_blank" >RIV/00216208:11120/12:00003517 - isvavai.cz</a>

Alternative codes found

RIV/00064173:_____/12:#0000240

Result on the web

<a href="http://dx.doi.org/10.1016/j.ahj.2011.10.007" target="_blank" >http://dx.doi.org/10.1016/j.ahj.2011.10.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ahj.2011.10.007" target="_blank" >10.1016/j.ahj.2011.10.007</a>

Result language

angličtina

Original language name

Rationale and design of The Coronary Artery Bypass Grafting Surgery Off or On Pump Revascularization Study: A large international randomized trial in cardiac surgery

Original language description

Uncertainty remains regarding the benefits and risks of the technique of operating on a beating heart (off pump) for coronary artery bypass grafting (CABG) surgery versus on-pump CABG. Prior trials had few events and relatively short follow-up. There isa need for a large randomized, controlled trial with long-term follow-up to inform both the short-and long-term impact of the 2 approaches to CABG. Methods We plan to randomize 4,700 patients in whom CABG is planned to undergo the procedure on pump or off pump. The coprimary outcomes are a composite of total mortality, myocardial infarction (MI), stroke, and renal failure at 30 days and a composite of total mortality, MI, stroke, renal failure, and repeat revascularization at 5 years. We will also undertake a cost-effectiveness analysis at 30 days and 5 years after CABG surgery. Other outcomes include neurocognitive dysfunction, recurrence of angina, cardiovascular mortality, blood transfusions, and quality of life. Results As of May 3,

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

American Heart Journal

ISSN

0002-8703

e-ISSN

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Volume of the periodical

163

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

1-6

UT code for WoS article

000298153000003

EID of the result in the Scopus database

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