Gastrointestinal Stromal Tumors (GIST): A Single Center Experience

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F12%3A43897432" target="_blank" >RIV/00216208:11120/12:43897432 - isvavai.cz</a>

Alternative codes found

RIV/00064173:_____/12:43897432

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Gastrointestinal Stromal Tumors (GIST): A Single Center Experience

Original language description

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal (GI) tract. They are believed to originate from the interstitial cells of Cajal (ICCs) or from the precursors of ICCs. Most GISTs show an activatingmutation in either the c-kit or platelet-derived growth factor receptor alpha (PDGFRA) gene. Tumor size, mitotic rate, and anatomic location correlate with potential malignancy and recurrence rate. A total of 12 patients were diagnosed to have GIST based on histology or immunohistochemistry of a biopsy or resection specimen obtained from the GI tract in the 2004-2009 period. The material was obtained using retrospective data collection. Tumors classified as GISTs with low and very low risk of progression are associated with a very good prognosis, with virtually all patients surviving 5 years. In patients with high risk or progressive diseases, the prognosis of 5-year survival is much poorer. The main therapeutic option is surgical remo

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FJ - Surgery including transplantology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Chirurgica Belgica

ISSN

0001-5458

e-ISSN

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Volume of the periodical

112

Issue of the periodical within the volume

1

Country of publishing house

BE - BELGIUM

Number of pages

7

Pages from-to

33-39

UT code for WoS article

000300603000007

EID of the result in the Scopus database

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