Extracellular Nucleic Acids in Maternal Circulation as Potential Biomarkers for Placental Insufficiency

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F12%3A43902581" target="_blank" >RIV/00216208:11120/12:43902581 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1089/dna.2011.1530" target="_blank" >http://dx.doi.org/10.1089/dna.2011.1530</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1089/dna.2011.1530" target="_blank" >10.1089/dna.2011.1530</a>

Result language
angličtina
Original language name
Extracellular Nucleic Acids in Maternal Circulation as Potential Biomarkers for Placental Insufficiency
Original language description
Since the placenta is being continuously remodeled during normal placental development, extracellular nucleic acids of both fetal and placental origin, packed into either trophoblast-derived apoptotic bodies or shedding syncytiotrophoblast microparticles, may be detected in maternal circulation during the course of normal gestation. Placental-insufficiency-related pregnancy complications have been shown to be associated with excessive placental trophoblast apoptosis and shedding of placenta debris. Recent advances in the field are reviewed with a focus on the diagnostic potential of particular molecular biomarkers and their eventual implementation in the currently used predictive and diagnostic algorithms for placental-insufficiency-related pregnancy complications
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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