The effect of site (deltoid or gluteus muscle) of intramuscular administration of anaesthetic drugs on the course of immobilisation in macaque monkeys (Macaca mulatta)

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F12%3A43906490" target="_blank" >RIV/00216208:11120/12:43906490 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/12:00058606
Result on the web
<a href="http://dx.doi.org/10.2754/avb201281020207" target="_blank" >http://dx.doi.org/10.2754/avb201281020207</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2754/avb201281020207" target="_blank" >10.2754/avb201281020207</a>

Result language
angličtina
Original language name
The effect of site (deltoid or gluteus muscle) of intramuscular administration of anaesthetic drugs on the course of immobilisation in macaque monkeys (Macaca mulatta)
Original language description
The aim of this work was to study the effect of site of intramuscular administration of anaesthetic drugs on the course of immobilisation in macaque monkeys (Macaca mulatta). Twenty macaque monkeys were given medetomidine (25 mu g.kg(-1)) and ketamine (3mg.kg(-1)) intramuscularly to the deltoid (n = 10 animals) or gluteus (n = 10 animals) muscles. Behavioural changes, loss of aggressiveness, immobilisation time and cardiorespiratory changes were recorded. The effect of drugs was reversed after 20 min by i.m. administration of atipamezole at the dose of 250 mu g.kg(-1). Highly significant differences (P < 0.001) were found between groups with gluteal or deltoid administration of drugs on the onset of immobilisation effect (71.3 s and 108.3 s, respectively), and immobilisation time (152.7 s and 254.4 s, respectively). In the gluteus muscle group, the grasp reflex was still present at the beginning of immobilisation and slowly wore off in 15-45 s. The same was valid for muscle tone. Ther
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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