Definitive radiochemotherapy with weekly cisplatin in patients with head and neck cancer; single institution outcome analysis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F12%3A43906591" target="_blank" >RIV/00216208:11120/12:43906591 - isvavai.cz</a>
Alternative codes found
RIV/00064211:_____/12:#0000213
Result on the web
<a href="http://www.ncbi.nlm.nih.gov/pubmed/23033284" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/23033284</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Definitive radiochemotherapy with weekly cisplatin in patients with head and neck cancer; single institution outcome analysis
Original language description
Purpose: The objective of this study was to evaluate the feasibility, toxicity and efficacy of definitive radiochemotherapy with weekly cisplatin in head and neck cancer in a single institutional setting. Methods: Previously untreated patients with stageII-IV head and neck cancer were included. Radiotherapy consisted of 70 Gy/7 weeks/35 fractions. All patients received concurrent cisplatin 40 mg/m(2) weekly Results: Between 2/2002 and 8/2009, 148 consecutive patients (WHO <= 2, male to female ratio 6/1, median age 56 years) were treated. The mean follow-up was 40 months. Tumors of the oropharynx were the most frequent (46%) and stage IV predominated (80%). Eighty-nine percent of the patients had received the full radiation treatment as planned. Omission of weekly cisplatin occurred frequently, mainly because of hematological toxicity. Only 64% of the patients completed at least 5 cycles of chemotherapy. Grade 3/4 mucosal toxicity developed in 32% of the patients. The late toxicities w
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of BUON
ISSN
1107-0625
e-ISSN
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Volume of the periodical
17
Issue of the periodical within the volume
3
Country of publishing house
GR - GREECE
Number of pages
7
Pages from-to
471-477
UT code for WoS article
000309793000010
EID of the result in the Scopus database
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