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Coefficient of Energy Balance: Effective Tool for Early Differential Diagnosis of CNS Diseases

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F13%3A43907502" target="_blank" >RIV/00216208:11120/13:43907502 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023001:_____/13:00058668 RIV/00064190:_____/13:#0000604

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Coefficient of Energy Balance: Effective Tool for Early Differential Diagnosis of CNS Diseases

  • Original language description

    Urgent examination of cerebrospinal fluid (CSF) provides immediate important information about the character of central nervous system (CNS) impairment. Although this examination includes energy parameters such as glucose and lactate concentrations, it does not commonly use Coefficient of Energy Balance (CEB). In this study, we focused on CEB because it enables more exact assessment of actual energy state in the CSF compartment than glucose and lactate alone. CEB informs about the actual functioning condition of present cells, and it does not require any other analysis or costs. Using Kruskal-Wallis ANOVA, we examined a large CSF sample (n = 8183) and we compared CEB values among groups with different cytological syndromes. We found a statistically significant difference of CEB between the group with granulocyte pleocytosis and the control group. These results indicate a high degree of anaerobic metabolism caused by the oxidative burst of neutrophils. Similarly, we found a statisticall

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EE - Microbiology, virology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    BioMed Research International

  • ISSN

    2314-6133

  • e-ISSN

  • Volume of the periodical

    -

  • Issue of the periodical within the volume

    Article ID 745943

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

    1-8

  • UT code for WoS article

    000321352900001

  • EID of the result in the Scopus database