Pretreatment with Prasugrel in Non-ST-Segment Elevation Acute Coronary Syndromes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F13%3A43907678" target="_blank" >RIV/00216208:11120/13:43907678 - isvavai.cz</a>
Alternative codes found
RIV/00064173:_____/13:#0000364 RIV/00023001:_____/13:00058799
Result on the web
<a href="http://dx.doi.org/10.1056/NEJMoa1308075" target="_blank" >http://dx.doi.org/10.1056/NEJMoa1308075</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1056/NEJMoa1308075" target="_blank" >10.1056/NEJMoa1308075</a>
Alternative languages
Result language
angličtina
Original language name
Pretreatment with Prasugrel in Non-ST-Segment Elevation Acute Coronary Syndromes
Original language description
Although P2Y(12) antagonists are effective in patients with non-ST-segment elevation (NSTE) acute coronary syndromes. We evaluated the effect of administering the P2Y(12) antagonist prasugrel at the time of diagnosis versus administering it after the coronary angiography if percutaneous coronary intervention (PCI) was indicated. We enrolled 4033 patients with NSTE acute coronary syndromes and a positive troponin level who were scheduled to undergo coronary angiography within 2 to 48 hours after randomization. Patients were randomly assigned to receive prasugrel before the angiography (pretreatment group) or placebo (control group). When PCI was indicated, an additional 30 mg of prasugrel was given in the pretreatment group at the time of PCI and 60 mgof prasugrel was given in the control group. The rate of the primary efficacy end point, a composite of death from cardiovascular causes, myocardial infarction, stroke, urgent revascularization, or glycoprotein IIb/IIIa inhibitor rescue t
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
New England Journal of Medicine
ISSN
0028-4793
e-ISSN
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Volume of the periodical
369
Issue of the periodical within the volume
11
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
999-1010
UT code for WoS article
000324304200009
EID of the result in the Scopus database
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