Effect of prenatal methamphetamine exposure and challenge dose of the same drug in adulthood on epileptiform activity induced by electrical stimulation in female rats

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F14%3A43907829" target="_blank" >RIV/00216208:11120/14:43907829 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.neuroscience.2013.10.069" target="_blank" >http://dx.doi.org/10.1016/j.neuroscience.2013.10.069</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.neuroscience.2013.10.069" target="_blank" >10.1016/j.neuroscience.2013.10.069</a>

Result language
angličtina
Original language name
Effect of prenatal methamphetamine exposure and challenge dose of the same drug in adulthood on epileptiform activity induced by electrical stimulation in female rats
Original language description
The aim of the present study was to examine the effect of prenatal MA exposure and the MA challenge dose in adulthood on epileptiform activity of female rats in respect of their estrous cycle. Adult female rats were examined by using a model of focal electrical stimulation as in our previous study. The present study demonstrates that the effect of prenatal MA exposure and challenge dose of the same drug on focally-induced epileptiform activity in adult female rats depends on the estrous cycle.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
<a href="/en/project/GAP303%2F10%2F0580" target="_blank" >GAP303/10/0580: What is the role of mesolimbic reward circuit in the long-term effect of prenatal methamphetamine exposure in rats?</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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