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Simple Method for Evaluation of Planum Temporale Pyramidal Neurons Shrinkage in Postmortem Tissue of Alzheimer Disease Patients

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F14%3A43908391" target="_blank" >RIV/00216208:11120/14:43908391 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023752:_____/14:43914557

  • Result on the web

    <a href="http://dx.doi.org/10.1155/2014/607171" target="_blank" >http://dx.doi.org/10.1155/2014/607171</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1155/2014/607171" target="_blank" >10.1155/2014/607171</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Simple Method for Evaluation of Planum Temporale Pyramidal Neurons Shrinkage in Postmortem Tissue of Alzheimer Disease Patients

  • Original language description

    We measured the length of the pyramidal neurons in the cortical layer III in four subregions of the planum temporale (transitions into superior temporal gyrus, Heschl's gyrus, insular cortex, and Sylvian fissure) in control group and Alzheimer disease patients. Our hypothesis was that overall length of the pyramidal neurons would be smaller in the Alzheimer disease group compared to controls and also there would be right-left asymmetry in both the control and Alzheimer disease groups. We found pyramidalneuron length asymmetry only in controls-in the transition into the Sylvian fissure-and the rest of the subregions in the control group and Alzheimer disease patients did not show size difference. However, control-Alzheimer disease group pyramidal neuron length comparison revealed (a) no length difference in superior temporal gyrus transition area, (b) reversal of asymmetry in the insular transition area with left insular transition significantly shorter in the Alzheimer disease group c

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GBP304%2F12%2FG069" target="_blank" >GBP304/12/G069: Project of excellence in the field of neuroscience</a><br>

  • Continuities

    S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    BioMed Research International

  • ISSN

    2314-6133

  • e-ISSN

  • Volume of the periodical

    2014

  • Issue of the periodical within the volume

    Article ID 607171

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    6

  • Pages from-to

    1-6

  • UT code for WoS article

    000332650900001

  • EID of the result in the Scopus database