Tolerability and Safety of the New Anti-Obesity Medications

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F14%3A43908712" target="_blank" >RIV/00216208:11120/14:43908712 - isvavai.cz</a>

Alternative codes found

RIV/00023761:_____/14:#0000454

Result on the web

<a href="http://dx.doi.org/10.1007/s40264-014-0206-3" target="_blank" >http://dx.doi.org/10.1007/s40264-014-0206-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s40264-014-0206-3" target="_blank" >10.1007/s40264-014-0206-3</a>

Result language

angličtina

Original language name

Tolerability and Safety of the New Anti-Obesity Medications

Original language description

Worldwide obesity prevalence has nearly doubled since 1980. Due to numerous co-morbidities, obesity represents a serious health and socioeconomic problem worldwide. Pharmacotherapy should be an integral part of comprehensive obesity management. Drug therapy can assist in weight loss and its maintenance in those individuals who do not achieve appropriate weight loss through lifestyle interventions alone. After the withdrawal of sibutramine from the market in 2010, orlistat, a lipase inhibitor, was the only remaining prescription drug approved for the long-term treatment of obesity. In 2012, phentermine/topiramate extended-release (PHEN/TPM ER) combination and lorcaserin were approved by the US FDA as novel medications for long-term weight management. Three major phase III trials conducted with each drug confirmed their efficacy in terms of weight loss/maintenance and improvement of cardiometabolic risks. No head-to-head studies between the two new anti-obesity drugs have been carried ou

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Drug Safety

ISSN

0114-5916

e-ISSN

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Volume of the periodical

37

Issue of the periodical within the volume

9

Country of publishing house

NZ - NEW ZEALAND

Number of pages

10

Pages from-to

693-702

UT code for WoS article

000344615000004

EID of the result in the Scopus database

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