The use of formalin-fixed, paraffin-embedded lymph node samples for the detection of minimal residual disease in mantle cell lymphoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43909289" target="_blank" >RIV/00216208:11120/15:43909289 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/15:10284263 RIV/00216208:11130/15:10284263 RIV/00179906:_____/15:10284263 RIV/00064173:_____/15:#0000471 and 2 more
Result on the web
<a href="http://dx.doi.org/10.1111/bjh.13182" target="_blank" >http://dx.doi.org/10.1111/bjh.13182</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/bjh.13182" target="_blank" >10.1111/bjh.13182</a>
Alternative languages
Result language
angličtina
Original language name
The use of formalin-fixed, paraffin-embedded lymph node samples for the detection of minimal residual disease in mantle cell lymphoma
Original language description
In the remaining cases, there is either no BM/PB infiltration or it is too low for the reliable identification of a clonal IGH target on the background of normal B lymphocytes. In those cases, a fresh diagnostic lymph node sample could serve for target identification and dilution series construction, but this is rarely available, especially in a multicentre setting. Here, we describe a method for MRD quantification based on FFPE tissue samples than can reliably detect MRD in MCL patients. The DNA was isolated from FFPE sections and checked for integrity via amplification of differently sized fragments and for amplificability via the ALB control gene.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT13072" target="_blank" >NT13072: Observational study for patients with newly diagnosed mantle cell lymphoma (MCL) not eligible for high-dose therapy according to the protocol alternating R-CHOP and R-cytarabine chemotherapy regimen (3+3 cycles)</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
British Journal of Haematology
ISSN
0007-1048
e-ISSN
—
Volume of the periodical
169
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
4
Pages from-to
145-148
UT code for WoS article
000351446400019
EID of the result in the Scopus database
2-s2.0-84925088787