Insulin resistance and outcome in bipolar disorder

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43909413" target="_blank" >RIV/00216208:11120/15:43909413 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1192/bjp.bp.114.152850" target="_blank" >http://dx.doi.org/10.1192/bjp.bp.114.152850</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1192/bjp.bp.114.152850" target="_blank" >10.1192/bjp.bp.114.152850</a>

Result language

angličtina

Original language name

Insulin resistance and outcome in bipolar disorder

Original language description

Background: Little is known about the impact of insulin resistance on bipolar disorder. Aims: To examine the relationships between insulin resistance, type 2 diabetes and clinical course and treatment outcomes in bipolar disorder. Method: We measured fasting glucose and insulin in 121 adults with bipolar disorder. We diagnosed type 2 diabetes and determined insulin resistance. The National Institute of Mental Health Life Chart was used to record the course of bipolar disorder and the Alda scale to establish response to prophylactic lithium treatment. Results: Patients with bipolar disorder and type 2 diabetes or insulin resistance had three times higher odds of a chronic course of bipolar disorder compared with euglycaemic patients (50% and 48.7% respectively v. 27.3%, odds ratio (OR) = 3.07, P = 0.007), three times higher odds of rapid cycling (38.5% and 39.5% respectively v. 18.2%, OR = 3.13, P = 0.012) and were more likely to be refractory to lithium treatment (36.8% and 36.7% respe

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

British Journal of Psychiatry

ISSN

0007-1250

e-ISSN

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Volume of the periodical

206

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

52-57

UT code for WoS article

000349656200010

EID of the result in the Scopus database

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