The impact of sleep disorders on glucose metabolism: endocrine and molecular mechanisms

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43909571" target="_blank" >RIV/00216208:11120/15:43909571 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1186/s13098-015-0018-3" target="_blank" >http://dx.doi.org/10.1186/s13098-015-0018-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s13098-015-0018-3" target="_blank" >10.1186/s13098-015-0018-3</a>

Result language

angličtina

Original language name

The impact of sleep disorders on glucose metabolism: endocrine and molecular mechanisms

Original language description

Modern lifestyle has profoundly modified human sleep habits. Sleep duration has shortened over recent decades from 8 to 6.5 hours resulting in chronic sleep deprivation. Additionally, irregular sleep, shift work and travelling across time zones lead to disruption of circadian rhythms and asynchrony between the master hypothalamic clock and pacemakers in peripheral tissues. Furthermore, obstructive sleep apnea syndrome (OSA), which affects 4 - 15% of the population, is not only characterized by impairedsleep architecture but also by repetitive hemoglobin desaturations during sleep. Epidemiological studies have identified impaired sleep as an independent risk factor for all cause of-, as well as for cardiovascular, mortality/morbidity. More recently, sleep abnormalities were causally linked to impairments in glucose homeostasis, metabolic syndrome and Type 2 Diabetes Mellitus (T2DM). This review summarized current knowledge on the metabolic alterations associated with the most prevalent

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

<a href="/en/project/GA13-27735S" target="_blank" >GA13-27735S: Modifications in Adipose Tissue Metabolism Leading to Diabetes in Sleep Apnea Syndrome (Study SAMET - Sleep Apnea and Adipose Tissue Metabolism)</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Diabetology &amp; Metabolic Syndrome

ISSN

1758-5996

e-ISSN

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Volume of the periodical

7

Issue of the periodical within the volume

-

Country of publishing house

GB - UNITED KINGDOM

Number of pages

16

Pages from-to

"Article 25"

UT code for WoS article

000352068600001

EID of the result in the Scopus database

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