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Minimum inhibitory concentrations of erythromycin and other antibiotics for Czech strains of Bordetella pertussis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43909610" target="_blank" >RIV/00216208:11120/15:43909610 - isvavai.cz</a>

  • Alternative codes found

    RIV/75010330:_____/15:00010821

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Minimum inhibitory concentrations of erythromycin and other antibiotics for Czech strains of Bordetella pertussis

  • Original language description

    Aim of the study: To test the susceptibility to first-line and alternative antibiotics of 70 Bordetella pertussis (B. pertussis) strains recovered from patients with whooping cough through national pertussis surveillance in the Czech Republic (CR) in 1967-2010. Material and methods: The minimum inhibitory concentrations (MICs) of erythromycin, clarithromycin, azithromycin, ciprofloxacin, and co-trimoxazole were tested by the reference agar dilution method on Bordet-Gengou agar with 15 % defibrinated sheep blood. Results: Each of the 70 study strains was inhibited by two concentrations of erythromycin and azithromycin (0.06 and 0.12 mg/l) and by three concentrations of clarithromycin (0.03, 0.06, and 0.12 mg/l), with the highest concentration of the MICrange being 0.12 mg/l for all these similar antibiotics. Tested in a 2-fold geometric dilution series, the concentration of erythromycin required to inhibit 90 % of the study strains (MIC90) was one dilution step lower (0.06 mg/l) than t

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FN - Epidemiology, infection diseases and clinical immunology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT14058" target="_blank" >NT14058: Study and comparison of the Bordetella pertussis strains isolated during the period 1964-2015 by molecular biological methods and applications of the results as the basis for the draft update of vaccination strategies in the Czech Republic</a><br>

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Epidemiologie, mikrobiologie, imunologie

  • ISSN

    1210-7913

  • e-ISSN

  • Volume of the periodical

    64

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    4

  • Pages from-to

    12-15

  • UT code for WoS article

    000353309200003

  • EID of the result in the Scopus database