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Renal risk associated with sodium phosphate medication: safe in healthy individuals, potentially dangerous in others

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43909862" target="_blank" >RIV/00216208:11120/15:43909862 - isvavai.cz</a>

  • Alternative codes found

    RIV/00064173:_____/15:#0000483

  • Result on the web

    <a href="http://dx.doi.org/10.1517/14740338.2015.1044970" target="_blank" >http://dx.doi.org/10.1517/14740338.2015.1044970</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1517/14740338.2015.1044970" target="_blank" >10.1517/14740338.2015.1044970</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Renal risk associated with sodium phosphate medication: safe in healthy individuals, potentially dangerous in others

  • Original language description

    The review presents complications associated with the use of agents containing sodium phosphate with regard to electrolyte disorders and renal impairment, namely acute phosphate nephropathy (APhN). This paper discusses the pathophysiology, histopathological findings, clinical symptoms, diagnosis and treatment of APhN. Additionally, it examines the epidemiology of adverse renal events and the safety of using sodium phosphate preparations prior to colonoscopy. EXPERT OPINION: Because of safety concerns, sodium phosphate purgatives are not recommended for routine bowel cleansing. Despite some serious and even fatal adverse events associated with these drugs when used with at-risk patients, available data suggest that administration of sodium phosphate purgatives is relatively safe in nonrisk individuals(i.e., in adequately hydrated, otherwise healthy adults, younger than 55 years with evidence of normal renal function).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FB - Endocrinology, diabetology, metabolism, nutrition

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Expert Opinion on Drug Safety

  • ISSN

    1474-0338

  • e-ISSN

  • Volume of the periodical

    14

  • Issue of the periodical within the volume

    7

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    14

  • Pages from-to

    1097-1110

  • UT code for WoS article

    000357547900008

  • EID of the result in the Scopus database