Cardiovascular and cerebrovascular disease associated microRNAs are dysregulated in placental tissues affected with pre-eclampsia and intrauterine growth restriction

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43910286" target="_blank" >RIV/00216208:11120/15:43910286 - isvavai.cz</a>

Alternative codes found

RIV/00023698:_____/15:N0000003

Result on the web

<a href="http://dx.doi.org/10.1371/journal.pone.0138383" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0138383</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1371/journal.pone.0138383" target="_blank" >10.1371/journal.pone.0138383</a>

Result language

angličtina

Original language name

Cardiovascular and cerebrovascular disease associated microRNAs are dysregulated in placental tissues affected with pre-eclampsia and intrauterine growth restriction

Original language description

To demonstrate that pregnancy-related complications are associated with alterations in cardiovascular and cerebrovascular microRNA expression. Gene expression of 32 microRNAs (miR-1-3p, miR-16-5p, miR-17-5p, miR-20a-5p, miR-20b-5p, miR-21-5p, miR-23a-3p,miR-24-3p, miR-26a-5p, miR-29a-3p, miR-33a-5p, miR-92a-3p, miR-100-5p, miR-103a-3p, miR-122-5p, miR-125b-5p, miR-126-3p, miR-130b-3p, miR-133a-3p, miR-143-3p, miR-145-5p, miR-146a-5p, miR-155-5p, miR-181a-5p, miR-195-5p, miR-199a-5p, miR-208a-3p, miR-210-3p, miR-221-3p, miR-342-3p, miR-499a-5p, and miR-574-3p) was assessed in placental tissues, compared between groups (35 gestational hypertension, 80 preeclampsia, 35 intrauterine growth restriction and 20 normal pregnancies) and correlated with the severity of the disease with respect to clinical signs, delivery date, and Doppler ultrasound parameters. Initially, selection and validation of endogenous controls for microRNA expression studies in placental tissues affected by pregnancy-r

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FK - Gynaecology and obstetrics

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

PLoS One

ISSN

1932-6203

e-ISSN

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Volume of the periodical

10

Issue of the periodical within the volume

9

Country of publishing house

US - UNITED STATES

Number of pages

27

Pages from-to

"e0138383"

UT code for WoS article

000361792100058

EID of the result in the Scopus database

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