Effects of psychostimulants on social interaction in adult male rats

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43910475" target="_blank" >RIV/00216208:11120/15:43910475 - isvavai.cz</a>

Alternative codes found

RIV/67985823:_____/15:00454140

Result on the web

<a href="http://dx.doi.org/10.1097/FBP.0000000000000148" target="_blank" >http://dx.doi.org/10.1097/FBP.0000000000000148</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/FBP.0000000000000148" target="_blank" >10.1097/FBP.0000000000000148</a>

Result language

angličtina

Original language name

Effects of psychostimulants on social interaction in adult male rats

Original language description

Psychostimulants are known to have a huge impact on different forms of social behaviour. The aim of the present study was to compare the effects of three different psychostimulants [amphetamine, cocaine and 3,4 methylenedimethoxyamphetamine (MDMA)] on social interaction (SI) in adult male rats. The SI test was performed in a familiar arena and under low-stress environmental conditions. Experimental animals received amphetamine (0.5, 1.0, 1.5 mg/kg), cocaine (0.5, 1.0, 1.5, 2.5, 5.0, 10.0 mg/kg) or MDMA(2.5, 5.0, 10 mg/kg) and control animals received saline (1 ml/kg) 45 min before the SI test. Time spent in SI (individual patterns of social behaviour) and nonsocial activities (locomotion and rearing) were video recorded and then analysed offline, withthe following results: (a) all doses of amphetamine decreased SI. Specifically, all doses of amphetamine decreased mutual sniffing, and the higher doses also decreased allo-grooming and following behaviours. (b) The higher doses of cocai

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Behavioural Pharmacology

ISSN

0955-8810

e-ISSN

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Volume of the periodical

26

Issue of the periodical within the volume

8, Spec. Iss.

Country of publishing house

GB - UNITED KINGDOM

Number of pages

10

Pages from-to

776-785

UT code for WoS article

000365552100007

EID of the result in the Scopus database

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