Vasa vasorum of the failed aorto-coronary venous grafts
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F18%3A43916680" target="_blank" >RIV/00216208:11120/18:43916680 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/18:10375915 RIV/00064173:_____/18:N0000102 RIV/00023001:_____/18:00076941
Result on the web
<a href="https://doi.org/10.1007/s00276-018-2036-y" target="_blank" >https://doi.org/10.1007/s00276-018-2036-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00276-018-2036-y" target="_blank" >10.1007/s00276-018-2036-y</a>
Alternative languages
Result language
angličtina
Original language name
Vasa vasorum of the failed aorto-coronary venous grafts
Original language description
PURPOSE: This study was designed to investigate the distribution of vasa vasorum in walls of failed aorto-coronary venous grafts. METHODS: Fifty-one diseased venous grafts harvested from 39 patients underwent qualitative histological evaluation. The morphology of the grade of the pathological changes and the extent of the vascularisation were examined, and related to the length of the interval between the primary surgery and the explantation. The obtained results were placed into five groups, substantially differing one from the other in morphology and vascularisation. RESULTS: The intervals between grafts implantation and explantation ranged from 1 day to 35 years. The onset of arterialization of the graft media was observed on average at 1 month after bypass implantation. During this same time period massive intimal hyperplasia and atherosclerosis occurred. Vasa vasorum proliferation from the adventitia to the outer layers of the media was first apparent between 7 and 24 months after implantation. Proliferation of the vasa vasorum throughout the entire atherosclerotic media and hyperplastic intima continued for a much longer time interval. CONCLUSION: No correlation between neoangiogenesis and age, sex or type of bypassed coronary branch was proven. Regarding the given findings, the authors believe that changes in hemodynamic conditions and endothelial trauma are primarily responsible for the development of graft disease and that vasa vasorum proliferation is only a secondary reaction to the structural changes of the graft wall. To what extent the frequently present pre-existing intimal hyperplasia of venous bypass grafts play in the development of graft disease remains questionable.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30106 - Anatomy and morphology (plant science to be 1.6)
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Surgical and Radiologic Anatomy
ISSN
0930-1038
e-ISSN
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Volume of the periodical
40
Issue of the periodical within the volume
7
Country of publishing house
DE - GERMANY
Number of pages
10
Pages from-to
769-778
UT code for WoS article
000434974100007
EID of the result in the Scopus database
2-s2.0-85046891297