Could mechanical thrombectomy replace thrombolysis in the treatment of acute and subacute limb ischemia?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F19%3A43917056" target="_blank" >RIV/00216208:11120/19:43917056 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.23736/S0026-4725.18.04770-9" target="_blank" >https://doi.org/10.23736/S0026-4725.18.04770-9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.23736/S0026-4725.18.04770-9" target="_blank" >10.23736/S0026-4725.18.04770-9</a>

Result language

angličtina

Original language name

Could mechanical thrombectomy replace thrombolysis in the treatment of acute and subacute limb ischemia?

Original language description

Acute limb ischemia is a vascular emergency defined as a sudden decrease in limb perfusion associated with a risk of loss of viability of the affected extremity. Surgical treatment (Fogarty thromboembolectomy) is indicated only in suprainguinal occlusions. Other cases of acute and subacute limb ischemia should be managed percutaneously. Catheter-based treatment involves local thrombolysis and percutaneous mechanical thrombectomy (PMT). There are several devices in use for PMT; of them, the Rotarex system appears to be the most useful. There are no randomized studies comparing thrombolysis and PMT. Only indirect comparison is possible. The immediate and long-term results of PMT using the Rotarex device are probably more favourable than those following thrombolysis. Particularly for older and polymorbid patients, it may be significant that PMT, in comparison with thrombolysis, can restore blood flow faster and in one session; no contraindications for PMT in contrast to potentially life-threatening complications in thrombolysis exist, and there is also no need for observation in intensive care unit after PMT. Hospital stay after PMT is shorter. There is only one exception when thrombolysis cannot be replaced by Rotarex PMT-in the case of crural arteries involvement-due to the catheter size. In our opinion, PMT is superior to thrombolysis in the treatment of acute and subacute limb ischemia. Thrombolysis should be considered only in special cases, e.g. in crural arteries occlusions or in failure of mechanical thrombectomy.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Minerva Cardioangiologica

ISSN

0026-4725

e-ISSN

—

Volume of the periodical

67

Issue of the periodical within the volume

3

Country of publishing house

IT - ITALY

Number of pages

12

Pages from-to

234-245

UT code for WoS article

000470998400007

EID of the result in the Scopus database

2-s2.0-85066481216