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Laser angioplasty of peripheral arteries: basic principles, current clinical studies and future directions

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F19%3A43917717" target="_blank" >RIV/00216208:11120/19:43917717 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.5152/dir.2019.18515" target="_blank" >https://doi.org/10.5152/dir.2019.18515</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5152/dir.2019.18515" target="_blank" >10.5152/dir.2019.18515</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Laser angioplasty of peripheral arteries: basic principles, current clinical studies and future directions

  • Original language description

    Percutaneous transluminal angioplasty (PTA) is a routine procedure for the treatment of peripheral arterial disease. However, its main limitation is late restenosis occurring at a 1-year rate of 5-60%. Restenosis arises from injury to the arterial wall including overstretching, compression and rupture of the atherosclerotic plaque during balloon inflation. It is hypothesised that better long-term angioplasty results are observed if atherosclerotic plaques are removed rather than compressed and fractured. Laser angioplasty is one method to remove atherosclerotic plaques. We discuss the principles of lasers, physical properties of laser light, history of laser angioplasty and effects of laser radiation on tissues. Large clinical studies using laser angioplasty are critically assessed. In comparison to conventional PTA, there are some advantages of laser angioplasty: easier passing of chronic and calcified occlusions and according to some studies, better short- and medium-term results regarding limb salvage and management of in-stent restenoses. The main drawback of laser angioplasty is that current laser catheters are not able to create a sufficiently wide channel in the occlusion, meaning that adjunctive balloon dilatation is still required. Thus, long-term data may be misleading. Basic and applied research should continue to focus on enlargement of plaque ablation.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30201 - Cardiac and Cardiovascular systems

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Diagnostic and Interventional Radiology

  • ISSN

    1305-3825

  • e-ISSN

  • Volume of the periodical

    25

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    TR - TURKEY

  • Number of pages

    6

  • Pages from-to

    392-397

  • UT code for WoS article

    000484265700009

  • EID of the result in the Scopus database

    2-s2.0-85071785330