Factors influencing balance improvement in multiple sclerosis rehabilitation: A pragmatic multicentric trial

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F20%3A43918397" target="_blank" >RIV/00216208:11120/20:43918397 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1016/j.rehab.2019.05.007" target="_blank" >https://doi.org/10.1016/j.rehab.2019.05.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.rehab.2019.05.007" target="_blank" >10.1016/j.rehab.2019.05.007</a>

Result language

angličtina

Original language name

Factors influencing balance improvement in multiple sclerosis rehabilitation: A pragmatic multicentric trial

Original language description

OBJECTIVES: Treatment for progressive multiple sclerosis (pMS) is a key area of research. To date, whether MS type and the rehabilitation setting are associated with worse or better response to rehabilitation is unclear. We aimed to understand the association between balance and MS type, in/outpatient treatment and specificity of the intervention. METHODS: We assessed 150 people with MS before and after in/outpatient rehabilitation. The Berg Balance Scale (BBS) was used to discriminate between responders (&gt;=+3-point improvement in BBS score; a clinically meaningful improvement) and non-responders to specific or non-specific balance rehabilitation. Factors associated with balance were analyzed by univariate and multivariable logistic regression analyses, estimating odds ratios (ORs) and 95% confidence intervals (CIs). RESULTS: Balance improved after rehabilitation: median (quartile 1 [Q1]-Q3) BBS score pre- and post-rehabilitation of 49 (45-53) and 52 (47-55) (P&lt;0.001). Univariate logistic analysis revealed a clinically meaningful improvement in balance associated with pMS (OR 2.21 [95% CI 1.09-4.05]), inpatient therapy (0.41 [0.19-0.84]), using a walking aid (1.68 [1.06-2.69]), and low baseline BBS score (0.86 [0.81-0.92]). On multivariable analysis, probability of improvement was similar for participants with pMS and the relapsing-remitting form but was associated with low baseline BBS score and specific treatment (OR 0.81 [95% CI 0.74-0.89] and 5.66 [1.79-21.5]). CONCLUSION: A clinically meaningful improvement in balance was more likely when MS individuals with moderate to high disability had specific exercises targeting balance, but MS type did not influence the outcome.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30210 - Clinical neurology

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Annals of Physical and Rehabilitation Medicine

ISSN

1877-0657

e-ISSN

—

Volume of the periodical

63

Issue of the periodical within the volume

2

Country of publishing house

FR - FRANCE

Number of pages

6

Pages from-to

93-98

UT code for WoS article

000525738200002

EID of the result in the Scopus database

2-s2.0-85080854369