The potential value of histological analysis of thrombi extracted through mechanical thrombectomy during acute ischemic stroke treatment
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F20%3A43920126" target="_blank" >RIV/00216208:11120/20:43920126 - isvavai.cz</a>
Alternative codes found
RIV/00064173:_____/20:N0000099
Result on the web
<a href="https://doi.org/10.14744/AnatolJCardiol.2020.81342" target="_blank" >https://doi.org/10.14744/AnatolJCardiol.2020.81342</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.14744/AnatolJCardiol.2020.81342" target="_blank" >10.14744/AnatolJCardiol.2020.81342</a>
Alternative languages
Result language
angličtina
Original language name
The potential value of histological analysis of thrombi extracted through mechanical thrombectomy during acute ischemic stroke treatment
Original language description
Studies on thrombus composition in acute stroke or acute myocardial infarction may help elucidate clot etiology and understand reperfusion success or failure. Moreover, such studies may certainly aid in the development of new technologies aimed at retrieving specific subtypes of thrombi; as a matter of fact, thrombus composition is suggested to influence the choice of techniques used during mechanical thrombectomy and plays a role in potential device and thrombus interaction. Over the years, histological analysis on the composition of thrombi causing ischemic stroke has proved to be a powerful tool to set standard prevention and treatment protocols. By isolating clot components, it is possible to provide a more accurate diagnosis and distinguish different stroke subtypes. Studies on histological clot composition support the theory that cryptogenic stroke can have a cardiogenic origin too. Components found in thrombi extracted from stroke patients support the importance of antithrombotic therapy in preventing and treating cerebral ischemia; however, more studies are needed to improve results in all types and subtypes of stroke. Hence, more research is required to further comprehend the role that platelets, fibrin, von Willebrand factor (vWF), and DNA play in relation to mechanical thrombectomy and recombinant tissue plasminogen activator (rtPA) resistance and to overcome certain limitations.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Anatolian Journal of Cardiology
ISSN
2149-2263
e-ISSN
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Volume of the periodical
23
Issue of the periodical within the volume
5
Country of publishing house
TR - TURKEY
Number of pages
6
Pages from-to
254-259
UT code for WoS article
000535232600005
EID of the result in the Scopus database
2-s2.0-85084932262