Prediction of the need for phototherapy during hospital stay in preterm infants by transcutaneous bilirubinometry
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F20%3A43920254" target="_blank" >RIV/00216208:11120/20:43920254 - isvavai.cz</a>
Alternative codes found
RIV/00023698:_____/20:N0000025
Result on the web
<a href="https://doi.org/10.1016/j.earlhumdev.2020.105029" target="_blank" >https://doi.org/10.1016/j.earlhumdev.2020.105029</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.earlhumdev.2020.105029" target="_blank" >10.1016/j.earlhumdev.2020.105029</a>
Alternative languages
Result language
angličtina
Original language name
Prediction of the need for phototherapy during hospital stay in preterm infants by transcutaneous bilirubinometry
Original language description
Background: Neonatal hyperbilirubinemia is a common condition that frequently requires treatment with phototherapy and less commonly by exchange transfusion, especially in preterm infants. It is important to identify and monitor infants at risk of severe unconjugated hyperbilirubinemia early in the postnatal period to instigate appropriate management plans. Aims: To evaluate transcutaneous bilirubinometry (TCB) as a screening tool at 24 and 48 h of age to predict the need for phototherapy during hospital stay in preterm infants. Study design: A single centre prospective cohort study in a level III perinatal centre. Subjects: Preterm infants (23(+0) to 36(+6) weeks of gestation) were eligible for enrolment. Outcome measures: Primary outcome was to assess the predictive value of TCB at 24 and 48 h of age for the need of phototherapy during hospital stay. Results: A total of 338 preterm infants were enrolled. The majority of infants (98.1%) born below 32 weeks of gestation required phototherapy. For infants born at > 31 + 6 weeks of gestation, TCB at 24 h of age >= 81 mu mol/l had sensitivity 83%, specificity 56%, positive predictive value (PPV) 54.7% and negative predictive value (NPV) 84%. TCB at 48 h of age >= 145 mu mol/l had sensitivity 65%, specificity 62%, PPV 24% and NPV 90%. Conclusion: TCB performed poorly at 24 and 48 h of age as a predictor of phototherapy during hospital stay in preterm infants. The negative predictive value of the test at 48 h of age might be helpful for infants born after 31 + 6 weeks of gestation.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30214 - Obstetrics and gynaecology
Result continuities
Project
—
Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Early Human Development
ISSN
0378-3782
e-ISSN
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Volume of the periodical
146
Issue of the periodical within the volume
July
Country of publishing house
IE - IRELAND
Number of pages
6
Pages from-to
"Article 105029"
UT code for WoS article
000539266000009
EID of the result in the Scopus database
2-s2.0-85086346854