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Predictors of exercise capacity in patients with atrial correction of transposition of great arteries

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F20%3A43920343" target="_blank" >RIV/00216208:11120/20:43920343 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/20:10413089 RIV/00064203:_____/20:10413089

  • Result on the web

    <a href="https://doi.org/10.4149/BLL_2020_087" target="_blank" >https://doi.org/10.4149/BLL_2020_087</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.4149/BLL_2020_087" target="_blank" >10.4149/BLL_2020_087</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Predictors of exercise capacity in patients with atrial correction of transposition of great arteries

  • Original language description

    OBJECTIVES: To examine the relationship of clinical, biochemical and imaging parameters to maximum oxygen uptake in patients after atrial correction of transposition of great arteries. BACKGROUND: Exercise tolerance is a key determinant of quality of life in patients with adult congenital heart disease. It is determined by a large scale of factors often different from general cardiology. METHODS: 86 consecutive patients after Senning correction of TGA were subjected to clinical and echocardiographic examination, Holter monitoring, blood tests of NT-proBNP, MRI of the heart and exercise test. Parameters of these examinations were correlated to VO2 max. RESULTS: The average age of patients was 28+-3.5 years. The average systemic right ventricular function determined by MRI was 51.9+-7.9 %. The average NT-proBPN was 124.3+-23.6 ng/l, VO2 max. 31.7+-6.5 ml/kg/min and the heart rate reserve 106+-24 /min. Neither systemic right ventricular systolic function nor NT-proBPN predicted VO2 max., whereas the heart rate reserve did (p=0.003). CONCLUSION: An inability to increase heart rate during exercise noted in a considerable number of patients after atrial switch of TGA caused a decreased exercise tolerance. It is not solely the global systolic function of either ventricle that infl uences the exercise performance, rather it is the ability to increase heart rate and overall cardiac output appropriately (Tab. 3, Fig. 6, Ref. 28).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30201 - Cardiac and Cardiovascular systems

Result continuities

  • Project

    <a href="/en/project/NT13408" target="_blank" >NT13408: Long-term results of transposition of the great arteries after Senning correction</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Bratislavské lekárske listy / Bratislava Medical Journal

  • ISSN

    0006-9248

  • e-ISSN

  • Volume of the periodical

    121

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    SK - SLOVAKIA

  • Number of pages

    6

  • Pages from-to

    527-532

  • UT code for WoS article

    000571574800001

  • EID of the result in the Scopus database

    2-s2.0-85088841931