Predictors of exercise capacity in patients with atrial correction of transposition of great arteries
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F20%3A43920343" target="_blank" >RIV/00216208:11120/20:43920343 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/20:10413089 RIV/00064203:_____/20:10413089
Result on the web
<a href="https://doi.org/10.4149/BLL_2020_087" target="_blank" >https://doi.org/10.4149/BLL_2020_087</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4149/BLL_2020_087" target="_blank" >10.4149/BLL_2020_087</a>
Alternative languages
Result language
angličtina
Original language name
Predictors of exercise capacity in patients with atrial correction of transposition of great arteries
Original language description
OBJECTIVES: To examine the relationship of clinical, biochemical and imaging parameters to maximum oxygen uptake in patients after atrial correction of transposition of great arteries. BACKGROUND: Exercise tolerance is a key determinant of quality of life in patients with adult congenital heart disease. It is determined by a large scale of factors often different from general cardiology. METHODS: 86 consecutive patients after Senning correction of TGA were subjected to clinical and echocardiographic examination, Holter monitoring, blood tests of NT-proBNP, MRI of the heart and exercise test. Parameters of these examinations were correlated to VO2 max. RESULTS: The average age of patients was 28+-3.5 years. The average systemic right ventricular function determined by MRI was 51.9+-7.9 %. The average NT-proBPN was 124.3+-23.6 ng/l, VO2 max. 31.7+-6.5 ml/kg/min and the heart rate reserve 106+-24 /min. Neither systemic right ventricular systolic function nor NT-proBPN predicted VO2 max., whereas the heart rate reserve did (p=0.003). CONCLUSION: An inability to increase heart rate during exercise noted in a considerable number of patients after atrial switch of TGA caused a decreased exercise tolerance. It is not solely the global systolic function of either ventricle that infl uences the exercise performance, rather it is the ability to increase heart rate and overall cardiac output appropriately (Tab. 3, Fig. 6, Ref. 28).
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
<a href="/en/project/NT13408" target="_blank" >NT13408: Long-term results of transposition of the great arteries after Senning correction</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Bratislavské lekárske listy / Bratislava Medical Journal
ISSN
0006-9248
e-ISSN
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Volume of the periodical
121
Issue of the periodical within the volume
8
Country of publishing house
SK - SLOVAKIA
Number of pages
6
Pages from-to
527-532
UT code for WoS article
000571574800001
EID of the result in the Scopus database
2-s2.0-85088841931