Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F20%3A43920568" target="_blank" >RIV/00216208:11120/20:43920568 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.tig.2020.08.014" target="_blank" >https://doi.org/10.1016/j.tig.2020.08.014</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.tig.2020.08.014" target="_blank" >10.1016/j.tig.2020.08.014</a>

Result language
angličtina
Original language name
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Original language description
Equivalent to a thousandth of the diameter of a human hair, severe acute respiratory syndrome coronavirus 2 (SARS-CoV)-2 is an average size for an enveloped virus. Its structural proteins Spike, Envelope, and Membrane, embedded in a host-derived lipid edifice, enclose a nucleocapsid, holding one of the longest RNA viral genomes.Hijacking host translational machinery, this single-stranded genome encodes two polyproteins, with self-cleavagecapacity for release of 16 nonstructural proteins representing an enzymatic medley that forms an impressivearmoury. While distinct from SARS-CoV and Middle East respiratory syndrome coronavirus, the SARS-CoV-2genome shares major identity with bat-SL-CoVZC45, although not enough for direct ancestry. A formidableinvader, SARS-CoV-2 binds to a constitutively expressed angiotensin-converting enzyme 2 receptor for multiorgan infection and host defence short-circuiting ability. Harbouring one of the hardest coronavirus membrane proteins,this novel virion maintains exclusive resilience in bodily fluids and external environments, necessitating complexstrategies for its eradication
Czech name
—
Czech description
—

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)