Evidence of a vegan diet for health benefits and risks - an umbrella review of meta-analyses of observational and clinical studies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F23%3A43923584" target="_blank" >RIV/00216208:11120/23:43923584 - isvavai.cz</a>
Alternative codes found
RIV/00064173:_____/23:43923584 RIV/75010330:_____/23:00014476
Result on the web
<a href="https://doi.org/10.1080/10408398.2022.2075311" target="_blank" >https://doi.org/10.1080/10408398.2022.2075311</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/10408398.2022.2075311" target="_blank" >10.1080/10408398.2022.2075311</a>
Alternative languages
Result language
angličtina
Original language name
Evidence of a vegan diet for health benefits and risks - an umbrella review of meta-analyses of observational and clinical studies
Original language description
To summarize and evaluate the evidence on the health impact of a vegan diet, we conducted an umbrella review of systematic reviews and meta-analyses. PubMed, Cochrane Library, Web of Science and Epistemonikos were searched up to September 2021. Meta-analyses were recalculated by using a random effects model. The certainty of evidence (CoE) was evaluated by the GRADE approach. For the general healthy population, a vegan diet was effective for reducing body weight [MD (95% CI): -2.52 kg (-3.06, -1.98), n = 8 RCTs; moderate CoE] and was associated with further health benefits (with low CoE), including a lower risk of cancer incidence [SRR (95% CI): 0.84 (0.75, 0.95), n = 2] and a trend for lower risk of all-cause mortality [SRR (95% CI): 0.87 (0.75, 1.01), n = 2], as well as lower ApoB levels [MD (95% CI): -0.19 mu mol/L (-0.23, -0.15), n = 7 RCTs). The findings suggested adverse associations for a vegan diet with risk of fractures [SRR (95% CI): 1.46 (1.03, 2.07), n = 3; low CoE]. For persons with diabetes or at high CVD risk, a vegan diet reduced measures of adiposity, total cholesterol, LDL and improved glycemic control (CoE moderate to low). A vegan diet may have the potential for the prevention of cardiometabolic health, but it may also impair bone health. More well-conducted primary studies are warranted.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30308 - Nutrition, Dietetics
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Critical Reviews in Food Science and Nutrition
ISSN
1040-8398
e-ISSN
1549-7852
Volume of the periodical
63
Issue of the periodical within the volume
29
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
9926-9936
UT code for WoS article
000796441100001
EID of the result in the Scopus database
2-s2.0-85130101517