Microdialysis as a tool for antibiotic assessment in patients with diabetic foot: a review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F23%3A43925430" target="_blank" >RIV/00216208:11120/23:43925430 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/23:00083930 RIV/00216208:11130/23:10462225
Result on the web
<a href="https://doi.org/10.3389/fendo.2023.1141086" target="_blank" >https://doi.org/10.3389/fendo.2023.1141086</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fendo.2023.1141086" target="_blank" >10.3389/fendo.2023.1141086</a>
Alternative languages
Result language
angličtina
Original language name
Microdialysis as a tool for antibiotic assessment in patients with diabetic foot: a review
Original language description
Diabetic foot is a serious late complication frequently caused by infection and ischaemia. Both require prompt and aggressive treatment to avoid lower limb amputation. The effectiveness of peripheral arterial disease therapy can be easily verified using triplex ultrasound, ankle-brachial/toe-brachial index examination, or transcutaneous oxygen pressure. However, the success of infection treatment is difficult to establish in patients with diabetic foot. Intravenous systemic antibiotics are recommended for the treatment of infectious complications in patients with moderate or serious stages of infection. Antibiotic therapy should be initiated promptly and aggressively to achieve sufficient serum and peripheral antibiotic concentrations. Antibiotic serum levels are easily evaluated by pharmacokinetic assessment. However, antibiotic concentrations in peripheral tissues, especially in diabetic foot, are not routinely detectable. This review describes microdialysis techniques that have shown promise in determining antibiotic levels in the surroundings of diabetic foot lesions.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Frontiers in Endocrinology
ISSN
1664-2392
e-ISSN
1664-2392
Volume of the periodical
14
Issue of the periodical within the volume
April
Country of publishing house
CH - SWITZERLAND
Number of pages
11
Pages from-to
1141086
UT code for WoS article
000978591500001
EID of the result in the Scopus database
2-s2.0-85158961029