Improving working memory by electrical stimulation and cross-frequency coupling
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F24%3A43927603" target="_blank" >RIV/00216208:11120/24:43927603 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21230/24:00380187 RIV/68407700:21460/24:00380187
Result on the web
<a href="https://doi.org/10.1186/s13041-024-01142-1" target="_blank" >https://doi.org/10.1186/s13041-024-01142-1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s13041-024-01142-1" target="_blank" >10.1186/s13041-024-01142-1</a>
Alternative languages
Result language
angličtina
Original language name
Improving working memory by electrical stimulation and cross-frequency coupling
Original language description
Working memory (WM) is essential for the temporary storage and processing of information required for complex cognitive tasks and relies on neuronal theta and gamma oscillations. Given the limited capacity of WM, researchers have investigated various methods to improve it, including transcranial alternating current stimulation (tACS), which modulates brain activity at specific frequencies. One particularly promising approach is theta-gamma peak-coupled-tACS (TGCp-tACS), which simulates the natural interaction between theta and gamma oscillations that occurs during cognitive control in the brain. The aim of this study was to improve WM in healthy young adults with TGCp-tACS, focusing on both behavioral and neurophysiological outcomes. Thirty-one participants completed five WM tasks under both sham and verum stimulation conditions. Electroencephalography (EEG) recordings before and after stimulation showed that TGCp-tACS increased power spectral density (PSD) in the high-gamma region at the stimulation site, while PSD decreased in the theta and delta regions throughout the cortex. From a behavioral perspective, although no significant changes were observed in most tasks, there was a significant improvement in accuracy in the 14-item Sternberg task, indicating an improvement in phonological WM. In conclusion, TGCp-tACS has the potential to promote and improve the phonological component of WM. To fully realize the cognitive benefits, further research is needed to refine the stimulation parameters and account for individual differences, such as baseline cognitive status and hormonal factors.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Molecular Brain
ISSN
1756-6606
e-ISSN
1756-6606
Volume of the periodical
17
Issue of the periodical within the volume
October
Country of publishing house
GB - UNITED KINGDOM
Number of pages
14
Pages from-to
72
UT code for WoS article
001324198900001
EID of the result in the Scopus database
2-s2.0-85205528712