The Role of Pharmacotherapy in the Management of Comorbidities
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F25%3A43928543" target="_blank" >RIV/00216208:11120/25:43928543 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1007/978-3-031-81802-8_18" target="_blank" >https://doi.org/10.1007/978-3-031-81802-8_18</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-031-81802-8_18" target="_blank" >10.1007/978-3-031-81802-8_18</a>
Alternative languages
Result language
angličtina
Original language name
The Role of Pharmacotherapy in the Management of Comorbidities
Original language description
This chapter covers the basic principles of clinical pharmacology, focusing on the elderly and the role of pharmacotherapy in patients with comorbid mental and physical illnesses. Consideration of pharmacokinetic processes (liberation, absorption, distribution, metabolism, and elimination) helps improve the efficacy and safety of pharmacological treatments, especially for patients with comorbidities and polypharmacy. Since drug-drug interactions (DDIs) are a significant source of adverse drug events, the identification of potential DDIs may also contribute to better treatment of patients with comorbidities. Depression and physical comorbidities are discussed in detail in this chapter because depression is one of the most commonly diagnosed psychiatric disorders, and it is highly prevalent in patients with physical illnesses. In addition, the treatment of somatic conditions can induce secondary depression, and antidepressant medications have various somatic adverse effects. These complexities are summarized based on current evidence and specific clinical recommendations to help guide decision-making about the pharmacologic treatment of depression with somatic comorbidities. The short section on schizophrenia with somatic comorbidities emphasizes that, in addition to cardiovascular and metabolic diseases, infectious diseases, particularly pulmonary infections, are linked to higher mortality rates compared to the general population.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
30215 - Psychiatry
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Comorbidity between Mental and Physical Disorders: Identification, Management and Treatment
ISBN
978-3-031-81801-1
Number of pages of the result
20
Pages from-to
411-430
Number of pages of the book
523
Publisher name
Springer
Place of publication
Basel, Cham
UT code for WoS chapter
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