Bral1: Its Role in Diffusion Barrier Formation and Conduction Velocity in the CNS

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F10%3A6064" target="_blank" >RIV/00216208:11130/10:6064 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/10:00348934 RIV/00023001:_____/10:00002195
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Bral1: Its Role in Diffusion Barrier Formation and Conduction Velocity in the CNS
Original language description
Brain-specific hyaluronan-binding link protein, Bral1, colocalizes and forms complexes with negatively charged extracellular matrix (ECM) proteins at the nodes of Ranvier in the myelinated white matter. The study report that the ECM no longer shows a nodal pattern and that CNS nerve conduction is markedly decreased in Bral1-deficient mice and the changes in the extracellular space diffusion parameters, measured by the real-time iontophoretic method and diffusion-weighted magnetic resonance imaging (MRI), suggest a reduction in the diffusion hindrances in the white matter of mutant mice.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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