Nitrites and nitrates in exhaled breath condensate in cystic fibrosis: relation to clinical parameters

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F13%3A10209798" target="_blank" >RIV/00216208:11130/13:10209798 - isvavai.cz</a>

Alternative codes found

RIV/00064203:_____/13:10209798 RIV/00216208:11150/13:10209798

Result on the web

<a href="http://dx.doi.org/10.4149/BLL_2013_105" target="_blank" >http://dx.doi.org/10.4149/BLL_2013_105</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4149/BLL_2013_105" target="_blank" >10.4149/BLL_2013_105</a>

Result language

angličtina

Original language name

Nitrites and nitrates in exhaled breath condensate in cystic fibrosis: relation to clinical parameters

Original language description

Objectives: To evaluate correlation of exhaled breath condensate (EBC) nitrite and nitrate concentrations with disease severity in cystic fibrosis (CF) patients. Background: Nitrites and nitrates are products of oxidative metabolism of nitric oxide. Impaired metabolism of nitric oxide plays a role in pathogenesis of CF. Methods: EBC was collected from 46 stable CF patients and from 21 healthy controls. EBC concentrations of nitrites and nitrates were correlated with parameters of lung disease and nutritional status and with systemic inflammatory markers. Results: EBC nitrates concentrations in CF patients were lower than in healthy subjects (5.8 vs 14.3 mu mol/l, p<0.001). They correlated positively with FEV1 (p=0.025) and serum albumin values (p=0.016) and negatively with chest radiograph Northern score (p=0.015) and serum C-reactive protein values (p=0.005). EEC nitrites concentrations in CF patients did not differ from those in healthy subjects and were not correlated to any studied

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FC - Pneumology

OECD FORD branch

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Project

<a href="/en/project/NR8304" target="_blank" >NR8304: The significance of inflammatory and oxidative stress biomarkers in exhaled breath condensate for progression of cystic fibrosis</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Bratislavske Lekarske Listy

ISSN

0006-9248

e-ISSN

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Volume of the periodical

114

Issue of the periodical within the volume

9

Country of publishing house

SK - SLOVAKIA

Number of pages

5

Pages from-to

503-507

UT code for WoS article

000330327300003

EID of the result in the Scopus database

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