Circulating C19MC MicroRNAs in Preeclampsia, Gestational Hypertension, and Fetal Growth Restriction

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F13%3A10209812" target="_blank" >RIV/00216208:11130/13:10209812 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/13:43907838 RIV/00064203:_____/13:10209812 RIV/00023698:_____/13:#0000140

Result on the web

<a href="http://dx.doi.org/10.1155/2013/186041" target="_blank" >http://dx.doi.org/10.1155/2013/186041</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2013/186041" target="_blank" >10.1155/2013/186041</a>

Result language

angličtina

Original language name

Circulating C19MC MicroRNAs in Preeclampsia, Gestational Hypertension, and Fetal Growth Restriction

Original language description

The objective of the study was to identify the profile of circulating C19MC microRNAs (miR-516-5p, miR-517*, miR-518b, miR-520a*, miR-520h, miR-525, and miR-526a) in patients with established preeclampsia (n = 63), fetal growth restriction (n = 27), andgestational hypertension (n = 23). We examined the correlation between plasmatic concentrations and expression levels of microRNAs and the severity of the disease with respect to clinical signs, requirements for the delivery, and Doppler ultrasound parameters. Using absolute and relative quantification approaches, increased extracellular C19MC microRNA levels (miR-516-5p, P = 0.037, P = 0.009; miR-517*, P = 0.033, P = 0.043; miR-520a*, P = 0.001, P = 0.009; miR-525, P = 0.026, P = 0.01; miR-526a, P = 0.03, P = 0.035) were detected in patients with preeclampsia. The association analysis pointed to no relationship between C19MC microRNA plasmatic concentrations and expression profile and identified risk factors for a poorer perinatal outc

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EC - Immunology

OECD FORD branch

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Project

<a href="/en/project/GAP304%2F12%2F1352" target="_blank" >GAP304/12/1352: Implication of placenta-specific microRNAs in maternal circulation for diagnosis and prediction of placental insufficiency</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Mediators of Inflammation

ISSN

0962-9351

e-ISSN

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Volume of the periodical

neuveden

Issue of the periodical within the volume

2013

Country of publishing house

GB - UNITED KINGDOM

Number of pages

12

Pages from-to

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UT code for WoS article

000327329800001

EID of the result in the Scopus database

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