Reprogramming of B cell acute lymphoblastic leukemia cells: Do we need to shoot a moving target?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10295813" target="_blank" >RIV/00216208:11130/15:10295813 - isvavai.cz</a>
Alternative codes found
RIV/00064203:_____/15:10295813
Result on the web
<a href="http://dx.doi.org/10.1073/pnas.1508680112" target="_blank" >http://dx.doi.org/10.1073/pnas.1508680112</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1073/pnas.1508680112" target="_blank" >10.1073/pnas.1508680112</a>
Alternative languages
Result language
angličtina
Original language name
Reprogramming of B cell acute lymphoblastic leukemia cells: Do we need to shoot a moving target?
Original language description
In a recent paper, McClellan et al. report that blasts from some precursor B cell acute lymphoblastic leukemia (B-ALL) cases transdifferentiate (reprogram) into nonmalignant cells. Although showing induced reprogramming in both Philadelphia chromosome-positive (Ph+) and PhMINUS SIGN cases, the authors concentrate on Ph+ leukemias, proposing reprogramming to be a possible therapeutic modality for this high-risk group of B-ALLs. Although the findings are highly interesting and relevant, we would like to raise several points of concern.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Proceedings of the National Academy of Sciences of the United States of America
ISSN
0027-8424
e-ISSN
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Volume of the periodical
112
Issue of the periodical within the volume
27
Country of publishing house
US - UNITED STATES
Number of pages
1
Pages from-to
"E3455"
UT code for WoS article
000357527600003
EID of the result in the Scopus database
2-s2.0-84935450420