Trimodal therapy for invasive bladder cancer: is it really equal to radical cystectomy?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10315703" target="_blank" >RIV/00216208:11130/15:10315703 - isvavai.cz</a>

Alternative codes found

RIV/00064203:_____/15:10315703

Result on the web

<a href="http://dx.doi.org/10.1097/MOU.0000000000000203" target="_blank" >http://dx.doi.org/10.1097/MOU.0000000000000203</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/MOU.0000000000000203" target="_blank" >10.1097/MOU.0000000000000203</a>

Result language

angličtina

Original language name

Trimodal therapy for invasive bladder cancer: is it really equal to radical cystectomy?

Original language description

Purpose of reviewTrimodal therapy (TMT) is considered the most effective bladder-sparing approach for muscle-invasive urothelial carcinoma of the bladder (MIBC) and an alternative to radical cystectomy. The purpose of this article was to review and summarize the current knowledge on the equivalence of TMT and radical cystectomy based on the recent literature.Recent findingsTMT consists of a maximal transuretral resection of the bladder, followed by a concurrent radiotherapy and chemotherapy, limiting salvage radical cystectomy to nonresponder tumors or muscle-invasive recurrence. In large population studies, less than 6% of the patients with nonmetastatic MIBC receive a chemoradiation therapy and this rate is stable. A growing body of evidence exists that TMT provides good oncologic outcomes with low morbidity when compared with radical cystectomy. TMT requires, however, a close follow-up because of the high risk of local recurrence and salvage radical cystectomy in up to 30% of the pa

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Current Opinion in Urology

ISSN

0963-0643

e-ISSN

—

Volume of the periodical

25

Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

476-482

UT code for WoS article

000364132200017

EID of the result in the Scopus database

2-s2.0-84942592096