Improved outcome for children and adolescent with acute lymphoblastic leukemia in the first decade of the 21st century: a report from the Slovak Republic

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10315842" target="_blank" >RIV/00216208:11130/15:10315842 - isvavai.cz</a>

Alternative codes found

RIV/00064203:_____/15:10315842

Result on the web

<a href="http://dx.doi.org/10.4149/neo_2015_098" target="_blank" >http://dx.doi.org/10.4149/neo_2015_098</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4149/neo_2015_098" target="_blank" >10.4149/neo_2015_098</a>

Result language

angličtina

Original language name

Improved outcome for children and adolescent with acute lymphoblastic leukemia in the first decade of the 21st century: a report from the Slovak Republic

Original language description

Our aim was to analyze event-free (EFS) and overall survival (OS) among children and adolescents with acute lymphoblastic leukemia (ALL) treated with International BFM Intercontinental trial (ALL IC 2002) therapy in the Slovak Republic. In total, 280 children and adolescent age 1 to 18 years were treated with ALL IC BFM 2002 based therapy from 2002 to 2012, which was divided into two periods. During 2002-2007, when patients were actively enrolled in the ALL IC-BFM 2002 trial, and during 2008-2012 when the trial was closed and patients were treated with the same therapy without randomization. Five-year EFS and OS rates were 79% (+/- 2.6%) and 86% (+/- 2.1%), respectively, similar to results obtained in the ALL-BFM 95 trial, which was the basis for ALL IC BFM 2002 therapy. The EFS (p<0.012) and OS (p<0.003) were significantly better than the prior Slovak experience in 1997-2001. Survival is improved in standard and intermediate risk groups, including those age 1 to 6 years, and older; wi

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neoplasma

ISSN

0028-2685

e-ISSN

—

Volume of the periodical

62

Issue of the periodical within the volume

5

Country of publishing house

SK - SLOVAKIA

Number of pages

9

Pages from-to

812-820

UT code for WoS article

000362389600017

EID of the result in the Scopus database

2-s2.0-84943651306