Seroprevalence of Epstein-Barr Virus, Cytomegalovirus, and Polyomaviruses in Children with Inflammatory Bowel Disease

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10315918" target="_blank" >RIV/00216208:11130/15:10315918 - isvavai.cz</a>

Alternative codes found

RIV/00064203:_____/15:10315918

Result on the web

<a href="http://dx.doi.org/10.1007/s10620-015-3764-z" target="_blank" >http://dx.doi.org/10.1007/s10620-015-3764-z</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10620-015-3764-z" target="_blank" >10.1007/s10620-015-3764-z</a>

Result language

angličtina

Original language name

Seroprevalence of Epstein-Barr Virus, Cytomegalovirus, and Polyomaviruses in Children with Inflammatory Bowel Disease

Original language description

Young age and thiopurine therapy are risk factors for lymphoproliferative disease among patients with inflammatory bowel disease (IBD). The aims of this study were to evaluate the prevalence of seropositivity for the Epstein-Barr virus (EBV) and human cytomegalovirus (CMV) among children and adolescents with IBD, to assess the viral load of EBV, CMV, and BK and JC polyomaviruses (BKV, JCV) in these patients, and to assess the influence of different therapeutic regimens on seroprevalence and viral load.Children who had been followed in our center were tested for EBV, CMV, BKV, and JCV in a cross-sectional study. One hundred and six children were included who had Crohn's disease (68 %), ulcerative colitis (29 %), and unclassified IBD (3 %). We found that 64 % of patients were EBV seropositive. The proportion of EBV seropositive patients increased during childhood. Azathioprine therapy (p = 0.003) was associated with EBV seropositivity in a multiple logistic regression model, after adjus

Czech name

—

Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FG - Paediatrics

OECD FORD branch

—

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Digestive Diseases and Sciences

ISSN

0163-2116

e-ISSN

—

Volume of the periodical

60

Issue of the periodical within the volume

11

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

3399-3407

UT code for WoS article

000363542700032

EID of the result in the Scopus database

2-s2.0-84945480824