Asthma management: A new phenotype-based approach using presence of eosinophilia and allergy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F17%3A10361656" target="_blank" >RIV/00216208:11130/17:10361656 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11140/17:10361656

Result on the web

<a href="http://dx.doi.org/10.1111/all.13165" target="_blank" >http://dx.doi.org/10.1111/all.13165</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/all.13165" target="_blank" >10.1111/all.13165</a>

Result language

angličtina

Original language name

Asthma management: A new phenotype-based approach using presence of eosinophilia and allergy

Original language description

Asthma is a heterogeneous disease. The Czech Pneumology and Allergology Societies commissioned 10 experts to review the literature and create joint national guidelines for managing asthma, reflecting this heterogeneity. The aim was to develop an easy-to-use diagnostic strategy as a rational approach to the widening opportunities for the use of phenotype-targeted therapy. The guidelines were presented on websites for public comments by members of both the societies. The reviewers&apos; comments contributed to creating the final version of the guidelines. The key hallmark of the diagnostic approach is the pragmatic concept, which assesses the presence of allergy and eosinophilia in each asthmatic patient. The guidelines define three clinically relevant asthma phenotypes: eosinophilic allergic asthma, eosinophilic nonallergic asthma and noneosinophilic nonallergic asthma. The resulting multifunctional classification describing the severity, level of control and phenotype is the starting point for a comprehensive treatment strategy. The level of control is constantly confronted with the intensity of the common stepwise pharmacotherapy, and the concurrently included phenotyping is essential for phenotype-specific therapy. The concept of the asthma approach with assessing the presence of eosinophilia and allergy provides a way for more precise diagnosis, which is a prerequisite for using widening options of personalized therapy.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30225 - Allergy

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Allergy

ISSN

0105-4538

e-ISSN

—

Volume of the periodical

72

Issue of the periodical within the volume

9

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

1279-1287

UT code for WoS article

000406970900002

EID of the result in the Scopus database

2-s2.0-85018313900