Detection of antigen-specific T cells in patients with neuroborreliosis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F17%3A10373871" target="_blank" >RIV/00216208:11130/17:10373871 - isvavai.cz</a>

Alternative codes found

RIV/00064211:_____/17:W0000035

Result on the web

<a href="http://www.prolekare.cz/en/epidemiology-article/detection-of-antigen-specific-t-cells-in-patients-with-neuroborreliosis-62699" target="_blank" >http://www.prolekare.cz/en/epidemiology-article/detection-of-antigen-specific-t-cells-in-patients-with-neuroborreliosis-62699</a>

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Detection of antigen-specific T cells in patients with neuroborreliosis

Original language description

There is a lack of laboratory tests in clinical practice that can detect the activity of borrelial infection. This was the reason for testing an antigen-specific T-cell detection method in patients with neuroborreliosis: the ELISPOT method, which is capable of detecting antigen-specific T lymphocytes in clinical conditions. A group of 32 patients (20 diagnosed with neuroborreliosis; NB) was examined using this commercial method (LymeSpot intrerferon-D Assay Kit (R)). Of these 20 NB patients, 10 were found to be positive and 10 negative; four of the five persons tested prior to the antibiotic treatment were positive. Eight patients served as the control group, giving four positive and four negative results. The results achieved so far appear to be unequivocal; still, the test could be expected: a) in non-specific clinical symptoms with borderline or negative proof of antibodies; b) in eraly stage of the disease; c) in the case of seropositivity and unequivocal clinical picture. The basic prerequisite for the clinical utilization of the method, however, is that it be thoroughly tested.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30303 - Infectious Diseases

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Epidemiologie, mikrobiologie, imunologie

ISSN

1210-7913

e-ISSN

—

Volume of the periodical

66

Issue of the periodical within the volume

4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

3

Pages from-to

210-212

UT code for WoS article

000423183300007

EID of the result in the Scopus database

2-s2.0-85041068743