Lost in Menopausal Transition: the Timing of Atherosclerosis Prevention in Women

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F17%3A10373903" target="_blank" >RIV/00216208:11130/17:10373903 - isvavai.cz</a>

Alternative codes found

RIV/00064203:_____/17:10373903 RIV/00023001:_____/17:00060311

Result on the web

<a href="http://www.biomed.cas.cz/physiolres/pdf/66/66_S39.pdf" target="_blank" >http://www.biomed.cas.cz/physiolres/pdf/66/66_S39.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Lost in Menopausal Transition: the Timing of Atherosclerosis Prevention in Women

Original language description

Advanced atherosclerotic changes can often resist even to very aggressive treatment. Although basic mechanisms of its origin and development are known, some important steps in this process are still waiting for more detailed explanation. Therefore, in addition to already proved aggressive lowering of LDL cholesterol, appropriate timing of atherosclerosis treatment is of the essence. Revealing different stages of atherosclerotic process, less or more sensitive to treatment is of primary importance; however, its detection is complicated by several facts including not exactly identifiable periods of quiescence and progression of atherosclerotic process. One of populations, study of which could add valuable information regarding this problem, are women in menopausal transition. Previously unsuccessful therapy with hormone replacement therapy is restudied with focus on the time of/after menopause. Now, it is supposed to be favorable in women soon, approximately less than 8 years, after menopause. In addition, the same principle - optimal timing of the intervention of traditional cardiovascular risk factors, especially lipids, could be also of importance. Therefore, menopausal transition could be optimal period for the intervention in women at risk. However, this approach is to be proved by evidence from controlled prospective studies focused on lifestyle and/or pharmacological intervention.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30105 - Physiology (including cytology)

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

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Volume of the periodical

66

Issue of the periodical within the volume

Supplement 1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

"S39"-"S45"

UT code for WoS article

000398620900005

EID of the result in the Scopus database

2-s2.0-85017153263