Apoptotic caspases cut down the immunogenicity of radiation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F19%3A10398348" target="_blank" >RIV/00216208:11130/19:10398348 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=pDbuSENRm6" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=pDbuSENRm6</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/2162402X.2019.1655364" target="_blank" >10.1080/2162402X.2019.1655364</a>
Alternative languages
Result language
angličtina
Original language name
Apoptotic caspases cut down the immunogenicity of radiation
Original language description
Caspases are known for their ability to precipitate apoptosis. Our findings indicate that accelerating the terminal inactivation of cells dying in response to radiation therapy limit their immunogenicity as a consequence of reduced type I interferon secretion. Thus, caspase inhibitors stand out as promising combinatorial partners to improve the immunogenicity of radiation therapy in the clinic.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30102 - Immunology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
OncoImmunology [online]
ISSN
2162-402X
e-ISSN
2162-402X
Volume of the periodical
8
Issue of the periodical within the volume
11
Country of publishing house
US - UNITED STATES
Number of pages
3
Pages from-to
nestrankovano
UT code for WoS article
000482512000001
EID of the result in the Scopus database
2-s2.0-85071303276