Comparison of outcomes between people with and without central cord syndrome

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F20%3A10411855" target="_blank" >RIV/00216208:11130/20:10411855 - isvavai.cz</a>

Alternative codes found

RIV/00064203:_____/20:10411855

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=FlFa3QwC3d" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=FlFa3QwC3d</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41393-020-0491-x" target="_blank" >10.1038/s41393-020-0491-x</a>

Result language

angličtina

Original language name

Comparison of outcomes between people with and without central cord syndrome

Original language description

Study design Retrospective analysis of prospectively collected data. Objective Central cord syndrome (CCS) is reported to have better outcomes than other cervical lesions, especially for ambulation and bladder recovery. However, a formal comparison between patients with CCS and other incomplete cervical spinal cord injuries (iCSCI) is lacking. Aim of the study is to investigate the neurological and functional outcomes in patients with or without CCS. Setting European Multicenter Study. Methods Data following SCI were derived from the European Multicenter Study about Spinal Cord Injury Database. CCS was diagnosed based on a difference of at least ten points of motor score in favour of the lower extremities. Patients were evaluated at 30 days, 6 months and 1 year from injury. The neurological and functional data were collected at each time point based on the International Standards for Neurological Classification of Spinal Cord injury (ISNSCI) and Spinal Cord Independence Measure (SCIM). Patients were selected with a matching procedure based on lesion severity, neurological level of injury (NLI) and age. Evaluation of the outcomes was performed by means of two-way Anova for repeated measures. Results The matching produced 110 comparable dyads. At all time points, upper extremity motor scores remained lower than lower extremity motor scores in CCS compared with iCSCI. With regard to daily life independence, both cohorts achieved comparable improvements in self-care sub-scores between T0 and T2 (6.6 +/- 6.5 in CCS vs 8.2 +/- 6.9 in iCSCI, p = 0.15) but this sub-score was significantly lower in CCS compared with iCSCI (3.6 +/- 5.2 in CCS vs 7.3 +/- 7.0 in iCSCI at T0, 13.7 +/- 6.2 vs 16.5 +/- 5.7 at T2), while the other sub-scores were comparable. Conclusions In contrast to previous reports, people with CCS have poorer outcomes of self-care ability compared with iCSCI.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30300 - Health sciences

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Spinal Cord

ISSN

1362-4393

e-ISSN

—

Volume of the periodical

58

Issue of the periodical within the volume

12

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

1263-1273

UT code for WoS article

000537363700002

EID of the result in the Scopus database

2-s2.0-85085927485