Cryopreserved amniotic membrane in chronic nonhealing wounds: a series of case reports

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F24%3A10471022" target="_blank" >RIV/00216208:11130/24:10471022 - isvavai.cz</a>

Alternative codes found

RIV/00064203:_____/24:10471022 RIV/00023884:_____/24:00009702 RIV/00216208:11110/24:10471022 RIV/00064165:_____/24:10471022

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=2v-_HXsQa1" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=2v-_HXsQa1</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10561-023-10100-5" target="_blank" >10.1007/s10561-023-10100-5</a>

Result language

angličtina

Original language name

Cryopreserved amniotic membrane in chronic nonhealing wounds: a series of case reports

Original language description

A case series of the use of amniotic membrane (AM) for treating chronic nonhealing wounds. It presents five cases of polymorbid patients with a total of nine chronic nonhealing wounds. The patient group consisted of four men and one woman with various comorbidities, aged 45-72 years. The mean initial wound size was 15.8 cm2, and the mean time from the onset of the wound to the first application of AM was 122 weeks. The wounds were caused by chronic venous insufficiency and/or peripheral arterial disease. Wounds were treated in a standardized protocol. AM was applied weekly in the first month and then every two weeks. Photo documentation of the wound and microbiological colonization was carried out at each visit. In three out of five patients, the AM treatment effectively promoted healing up to complete wound closure. In two cases, the wounds stayed unhealed despite numerous AM applications. Pain relief was noted in all patients. The success of the treatment was closely tied to patient factors, such as adherence to the prescribed treatment regimen and individual patient characteristics. In some cases, treatment failure was observed, possibly due to underlying comorbidities, wound parameters, or poor patient compliance. AM treatment has the potential to become a viable treatment option for these nonhealing wounds. However, the effectiveness of the treatment may be influenced by various patient factors and the underlying cause of the wound. Therefore, it is crucial to have an individualized treatment plan that considers these particular factors.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

<a href="/en/project/NV18-08-00106" target="_blank" >NV18-08-00106: Amniotic membrane in the treatment of non-healing wounds.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cell and Tissue Banking

ISSN

1389-9333

e-ISSN

—

Volume of the periodical

25

Issue of the periodical within the volume

1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

13

Pages from-to

325-337

UT code for WoS article

001098909900001

EID of the result in the Scopus database

2-s2.0-85176014681