Sleep Disorders and Cognitive Aging among Cognitively Impaired vs. Unimpaired Older Adults
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F24%3A10471069" target="_blank" >RIV/00216208:11130/24:10471069 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=1NmnhtlCP1" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=1NmnhtlCP1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/geront/gnad152" target="_blank" >10.1093/geront/gnad152</a>
Alternative languages
Result language
angličtina
Original language name
Sleep Disorders and Cognitive Aging among Cognitively Impaired vs. Unimpaired Older Adults
Original language description
BACKGROUND AND OBJECTIVES: Sleep disorders often predict or co-occur with cognitive decline. Yet, little is known how the relationship unfolds among older adults at risk for cognitive decline.To examine the associations of sleep disorders with cognitive decline in older adults with unimpaired cognition, or impaired cognition (mild cognitive impairment [MCI] and dementia). RESEARCH DESIGN AND METHODS: 5,822 participants (Mage=70) of the National Alzheimer's Coordinating Center database with unimpaired or impaired cognition were followed for three subsequent waves. Four types of clinician-diagnosed sleep disorders were reported: sleep apnea, hyposomnia/insomnia, REM sleep behavior disorder, or "other." Cognition over time was measured by the Montreal Cognitive Assessment (MoCA) or an estimate of general cognitive ability (GCA) derived from scores based on 12 neuropsychological tests. Growth curve models were estimated adjusting for covariates. RESULTS: In participants with impaired cognition, baseline sleep apnea was related to better baseline MoCA performance (b=0.65, 95%CI=[0.07, 1.23]) and less decline in GCA over time (b=0.06, 95%CI=[0.001, 0.12]). Baseline insomnia was related to better baseline MoCA (b=1.54, 95%CI=[0.88, 2.21]) and less decline in MoCA over time (b=0.56, 95%CI=[0.20, 0.92]). Furthermore, having more sleep disorders (across the four types) at baseline predicted better baseline MoCA and GCA, and less decline in MoCA and GCA over time. These results were only found in those with impaired cognition and generally consistent when using self-reported symptoms of sleep apnea or insomnia. DISCUSSION AND IMPLICATIONS: Participants with sleep disorder diagnoses may have better access to healthcare, which may help maintain cognition through improved sleep.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30227 - Geriatrics and gerontology
Result continuities
Project
<a href="/en/project/LX22NPO5107" target="_blank" >LX22NPO5107: National institute for Neurological Research</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
The Gerontologist
ISSN
0016-9013
e-ISSN
1758-5341
Volume of the periodical
64
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
gnad152
UT code for WoS article
001107672300001
EID of the result in the Scopus database
2-s2.0-85190832659