The gray area of RQ-PCR-based measurable residual disease: subdividing the "positive, below quantitative range" category

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F24%3A10480422" target="_blank" >RIV/00216208:11130/24:10480422 - isvavai.cz</a>
Alternative codes found
RIV/00064203:_____/24:10480422
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=E63ZIoEzFz" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=E63ZIoEzFz</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41375-024-02265-z" target="_blank" >10.1038/s41375-024-02265-z</a>

Result language
angličtina
Original language name
The gray area of RQ-PCR-based measurable residual disease: subdividing the "positive, below quantitative range" category
Original language description
Detection of measurable residual disease (MRD) in hematological malignancies is crucial for prognostication and treatment decisions. Real-time quantitative PCR (RQ-PCR), which targets immunoglobulin (IG) and T-cell receptor (TR) rearrangements, is deemed the gold-standard method for MRD detection in national and international clinical trials. However, this approach does have some limitations, primarily related to standard curve performance and non-specific background amplification.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30205 - Hematology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)