Diagnosis of Alzheimer's Disease in Clinical Practice: Time to Incorporate Biomarkers?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F24%3A10485000" target="_blank" >RIV/00216208:11130/24:10485000 - isvavai.cz</a>
Alternative codes found
RIV/00064203:_____/24:10485000
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=ve7Bk7zju1" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=ve7Bk7zju1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3233/JAD-240660" target="_blank" >10.3233/JAD-240660</a>
Alternative languages
Result language
angličtina
Original language name
Diagnosis of Alzheimer's Disease in Clinical Practice: Time to Incorporate Biomarkers?
Original language description
Hippocampal dysfunction is associated with early clinical signs of Alzheimer's disease (AD). Due to the limited availability or invasiveness of current biomarkers, the AD diagnosis is usually based on cognitive assessment and structural brain imaging. The recent study by Lalive and colleagues examined the specificity of brain morphometry for the AD diagnosis in a memory clinic cohort with hippocampal-type amnestic syndrome. The results indicate that memory deficits and hippocampal atrophy are similar in AD and non-AD patients, highlighting their low diagnostic specificity. These findings challenge the traditional AD diagnosis and underscore the need for biomarkers to differentiate specific neuropathological entities.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Alzheimer's Disease
ISSN
1387-2877
e-ISSN
1875-8908
Volume of the periodical
101
Issue of the periodical within the volume
4
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
4
Pages from-to
1133-1136
UT code for WoS article
001362246900009
EID of the result in the Scopus database
2-s2.0-85206122748