Impact of Childhood Adversity on Late-Life Cognition in Older Puerto Rican Adults

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F25%3A10488848" target="_blank" >RIV/00216208:11130/25:10488848 - isvavai.cz</a>

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=_Hl6m15fFJ" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=_Hl6m15fFJ</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/geronb/gbae199" target="_blank" >10.1093/geronb/gbae199</a>

Result language

angličtina

Original language name

Impact of Childhood Adversity on Late-Life Cognition in Older Puerto Rican Adults

Original language description

OBJECTIVES: This study examined the association between childhood adversity and late-life cognitive outcomes among older Puerto Rican adults. METHODS: Data were from the PREHCO study, a population-based cohort of 3,713 older Puerto Rican adults (mean age 72.5 years; 60% female). Adverse childhood experiences (ACEs) were categorised into four factors: economic hardship, parental illiteracy, childhood illness, and neighbourhood disadvantage. Cognition was assessed with the Mini-Mental Cabán (MMC). For our analyses, cognitive impairment was defined as scoring 1.5 SD below expected score, adjusted for age, sex, education, and reading ability. Ordinal logistic regression (baseline) and generalised linear mixed models (all three waves) analysed MMC scores; generalised estimating equations assessed incident cognitive impairment (waves 2 and 3). RESULTS: All four adversity factors were associated with poorer MMC scores at baseline. Parental illiteracy (β=-0.35, p&lt;.001) and neighbourhood disadvantage (β=-0.27, p&lt;.001) showed stronger associations than economic hardship (β=-0.10, p=.003) and childhood illness (β=-0.21, p&lt;.001). No factors were significantly related to changes in cognitive scores over time. Depressive symptoms and self-rated health partially mediated cross-sectional relationships, with depressive symptoms showing a stronger effect. All adversity factors except economic hardship were linked to baseline cognitive impairment (OR=1.42 parent illiteracy, OR=1.24 childhood illness, OR=1.82 neighbourhood disadvantage, p&lt;.05). Only neighbourhood disadvantage was associated with incident cognitive impairment (OR=1.19, p=.003). DISCUSSION: This study highlights the lasting impact of childhood adversity on late-life cognitive health among older Puerto Ricans, suggesting that addressing early adversity may promote cognitive health later in life.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

<a href="/en/project/LX22NPO5107" target="_blank" >LX22NPO5107: National institute for Neurological Research</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journals of Gerontology - Series B Psychological Sciences and Social Sciences

ISSN

1079-5014

e-ISSN

1758-5368

Volume of the periodical

80

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

gbae199

UT code for WoS article

001482377700001

EID of the result in the Scopus database

2-s2.0-105002429909